ORIGINAL_SCIENTIFIC_ARTICLE Myxomatous mitral valve disease (MMVD) is one of the most common heart diseases in dogs. The disease progresses faster in Cavalier King Charles Spaniel (CKCS) dogs and occurs at an earlier age. QT interval length reflects abnormalities in ventricular repolarization which may predispose to the formation of fatal arrhythmias such as torsades de pointes. A fast and accurate assessment is therefore essential. The study aimed to examine the changes in QT duration in MMVD cases of CKCS and to calculate the corrected QT durations with Bazett’s formula in various stages of the disease. The study included 20 CKCS dogs of both genders, various ages and weights, and different stages of MMVD (n=6 in B1 stage, n=6 in B2 stage, and n=8 in C stage), and 5 healthy CKCS which were included in the control group. Clinical, radiological, hematological, biochemical, echocardiographic, and electrocardiographic examinations were performed. The corrected QT interval duration in the MMVD group was longer than the control (p<0.05). However, there was no significant difference between B1, B2, and C. It was concluded that the corrected QT interval can give a significant distinction between healthy and MMVD CKCS dogs. https://macvetrev.mk/LoadArticlePdf/362 2023-3-15 61 67 10.2478/macvetrev-2023-0014 Cavalier myxomatous mitral valve QT Hande Sağoğlu false 1 Department of Internal Medicine, Faculty of Veterinary Medicine,Istanbul University - Cerrahpaşa, 34320 Istanbul, Türkiye AUTHOR Remzi Gönül gonul@iuc.edu.tr false 2 Department of Internal Medicine, Faculty of Veterinary Medicine,Istanbul University - Cerrahpaşa, 34320 Istanbul, Türkiye LEAD_AUTHOR Lora Koenhemsi false 3 Department of Internal Medicine, Faculty of Veterinary Medicine,Istanbul University - Cerrahpaşa, 34320 Istanbul, Türkiye AUTHOR Emine Merve Alan false 4 Department of Internal Medicine, Faculty of Veterinary Medicine,Istanbul University - Cerrahpaşa, 34320 Istanbul, Türkiye AUTHOR Suzan Murat false 5 Department of Internal Medicine, Faculty of Veterinary Medicine,Istanbul University - Cerrahpaşa, 34320 Istanbul, Türkiye AUTHOR Ashkan Seddigh Nia false 6 Department of Internal Medicine, Faculty of Veterinary Medicine,Istanbul University - Cerrahpaşa, 34320 Istanbul, Türkiye AUTHOR Mehmet Erman Or false 7 Department of Internal Medicine, Faculty of Veterinary Medicine,Istanbul University - Cerrahpaşa, 34320 Istanbul, Türkiye AUTHOR Parker, H.G., Kilroy-Glynn, P. 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