ORIGINAL_ARTICLE The objective of this study was to determine the physiological effects of detomidine on Pateri goats. A total of six female Pateri goats were randomly treated with three different dose rates of Detomidine at 40 μg, 50 μg and 60 μg/kg body weights. The effects of Detomidine on respiratory and heart rate, rectal temperature and serum glucose level were investigated. Following detomidine intravenous administration in goats, it produced dose dependent effect on physiological parameters. Respiratory and heart rate decreased after intravenous administration in all goats. The heart rate decreased at 5 min with all dose rates and returned to the base line at 60 min. This change in heart rate was dose dependent and there was no significant (P>0.05) change observed with 40 μg and 50 μg/kg of Detomidine. However, there was significant difference (P<0.05) at 75 min between the 40 μg and 60 μg/kg of Detomidine in all goats. However, significant (P<0.01) increase in serum glucose level occurred with all dose rates at 30 min compared with control groups. It is concluded that Detomidine has produced no adverse effect on physiological parameters. https://macvetrev.mk/Files/Article/2020/10.1515/macvetrev-2015-0070/macvetrev-2015-0070.pdf 2016-03-15T09:00:00 77 81 10.2478/macvetrev-2015-0070 Pateri goat detomidine respiratory rate heart rate glucose Ahmed Tunio ahmedtuniodvm2009@gmail.com false 1 Faculty of Animal Husbandry and Veterinary Sciences,Sindh Agriculture University, Tandojam 70060, Pakistan LEAD_AUTHOR Shamasuddin Bughio false 2 Faculty of Animal Husbandry and Veterinary Sciences,Sindh Agriculture University, Tandojam 70060, Pakistan AUTHOR Jam Kashif Sahito false 3 Faculty of Animal Husbandry and Veterinary Sciences,Sindh Agriculture University, Tandojam 70060, Pakistan AUTHOR Muhammad Ghiasuddin Shah false 4 Faculty of Animal Husbandry and Veterinary Sciences,Sindh Agriculture University, Tandojam 70060, Pakistan AUTHOR Mahdi Ebrahimi false 5 Faculty of Veterinary Medicine, Universiti Putra Malaysia AUTHOR Shazia Parveen Tunio false 6 Social Science Research Institute, Tandojam, Pakistan AUTHOR Grimsrud, K. 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