Original Scientific Article
Hematological and biochemical parameters in symptomatic and asymptomatic leishmania-seropositive dogs
Igor Ulchar
*
,
Irena Celeska
,
Jovana Stefanovska
,
Anastasija Jakimovska
Received: 16 April 2015
Received in revised form: 22 May 2015
Accepted: 28 May 2015
Available Online First: 09 June 2015
Published on: 15 October 2015
Correspondence: Igor Ulchar, iulcar@fvm.ukim.edu.mk
Abstract
Leishmaniosis caused by Leishmania infantum is vector-born severe enzootic disease in dogs. It includes a wide spectrum of clinical symptoms, but the most characteristic are alterations in the hematopoetic system and renal failure. Also, infected animals could be asymptomatic, so the manifestation of L. infantum infection depends on many factors, including host’s immunological status. The aim of this survey was to find parameters related with hematopoetic and renal failure (hematology, biochemical parameters – urea, creatinine, serum proteins) in symptomatic and asymptomatic dogs seropositive for canine leishmaniosis. Within the hematological parameters, we found significant differences between symptomatic and asymptomatic dogs in the erythrogram and platelet count, but not in the leukogram. Significant differences between the two groups were found also for urea, creatinine, serum albumin and globulin, but not in serum total protein and A/G ratio. These findings indicate individual variability of the host’s response to infection with L. infantum.
Keywords: leishmaniosis, dog, hematology, biochemistry
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Copyright
© 2015 Ulchar I. This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non Commercial License (http://creativecommons.org), which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited.
Conflict of Interest Statement
The authors declared that they have no potential conflict of interest with respect to the authorship and/or publication of this article.
Citation Information
Macedonian Veterinary Review. Volume 38, Issue 2, Pages 175-182, p-ISSN 1409-7621, e-ISSN 1857-7415, DOI: 10.14432/j.macvetrev.2015.06.045, 2015
10.14432/j.macvetrev.2015.06.045
