Original Scientific Article
Observation of physiological changes after Detomidine administration in Pateri goat
Ahmed Tunio * ,
Shamasuddin Bughio ,
Jam Kashif Sahito ,
Muhammad Ghiasuddin Shah ,
Mahdi Ebrahimi ,
Shazia Parveen Tunio

Mac Vet Rev 2016; 39 (1): 77 - 81

10.1515/macvetrev-2015-0070

Received: 25 June 2015

Received in revised form: 19 October 2015

Accepted: 03 December 2015

Available Online First: 14 December 2015

Published on: 15 March 2016

Correspondence: Ahmed Tunio, ahmedtuniodvm2009@gmail.com
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Abstract

The objective of this study was to determine the physiological effects of detomidine on Pateri goats. A total of six female Pateri goats were randomly treated with three different dose rates of Detomidine at 40 μg, 50 μg and 60 μg/kg body weights. The effects of Detomidine on respiratory and heart rate, rectal temperature and serum glucose level were investigated. Following detomidine intravenous administration in goats, it produced dose dependent effect on physiological parameters. Respiratory and heart rate decreased after intravenous administration in all goats. The heart rate decreased at 5 min with all dose rates and returned to the base line at 60 min. This change in heart rate was dose dependent and there was no significant (P>0.05) change observed with 40 μg and 50 μg/kg of Detomidine. However, there was significant difference (P<0.05) at 75 min between the 40 μg and 60 μg/kg of Detomidine in all goats. However, significant (P<0.01) increase in serum glucose level occurred with all dose rates at 30 min compared with control groups. It is concluded that Detomidine has produced no adverse effect on physiological parameters.

Keywords: Pateri goat, detomidine, respiratory rate, heart rate, glucose

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Copyright

© 2015 Tunio A. This is an open-access article publishedunder the terms of the Creative Commons Attribution License whichpermits unrestricted use, distribution, and reproduction in any medium,provided the original author and source are credited.

Conflict of Interest Statement

The authors declared that they have no potential conflict of interest with respect to the authorship and/or publication of this article.

Citation Information

Macedonian Veterinary Review. Volume 39, Issue 1, Pages 77-81, p-ISSN 1409-7621, e-ISSN 1857-7415, DOI: 10.1515/macvetrev-2015-0070, 2016

The all content of the Macedonian Veterinary Review, except where otherwise noted, is licensed under a Creative Commons Attribution License.