Original Scientific Article
Alegic skin test method for diagnosis of bruceila infections in small ruminants
S. Mrenoski * ,
E. Rapoport ,
M. Banai ,
Liljana Petrovska ,
Z. Markic

Mac Vet Rev 1998; 27 (1): 55 - 58

619.636.3].616.98.579.841.93083.3

Received: 15 October 1998

Received in revised form: 15 October 1998

Accepted: 15 October 1998

Available Online First: 15 October 1998

Published on: 15 October 1998

Correspondence: S. Mrenoski,
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Abstract

Because the clinical signs of the brucellosis in small ruminants are not patognomonic and therefore diagnosis based on clinical symptoms is nontennable, additional laboratory tests are used for diagnostic of Brucella disease. Laboratory tests involve identification of the causative microorganism by classical laboratory techniques for isolation of Brucella spp. or PCR (Polymerase Chain Reaction) and measuring of the immune responses. Animals infected with Bruce/la spp. are usually diagnosed by serological tests, which measure the humoral immune response. Beside the humoral response, the infection with Bruce/la spp elicits cell-mediated immune response which can be detected by allergic skin test. Evaluation of the role of the cellmediated immune response in infection by Bruce/la spp. and its detection, using delayed type of hypersensitivity reaction, is described in this paper.

Keywords: brucellosis, small ruminants, cellular immune response, allergic skin test


References


Citation Information

Macedonian Veterinary Review. Volume 27, Issue 1-2, Pages 55-58, p-ISSN 1409-7621, 1998