Review Article
Porcine circovirus diseases
Ristoski Trpe * ,
Cvetkovic Iskra ,
Segales Joaquim

Mac Vet Rev 2009; 32 (1): 5 - 11

636.4.09.616.98.578

Received: 15 March 2009

Received in revised form: 15 March 2009

Accepted: 15 March 2009

Available Online First: 15 March 2009

Published on: 15 March 2009

Correspondence: Ristoski Trpe, tristoski@fvm.ukim.edu.mk
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Abstract

Porcine circovirus type 2 belongs on the family Circoviridae. This virus family includes small, non-enveloped viruses, with a circular, single-standed DNA genome.This virus causes mainly subclinical infections, but a number of diseases have been linked to it (porcine circovirus diseases, PCVD). The most economically important PCVD is postweaning multisystemic wasting syndrome (PMWS), which mainly affects pigs of 2 to 5 months of age, with progressive wasting, diarrhea and respiratory disorders. Main PMWS lesions are found in lymphoid tissues, which are characterized by lymphocyte depletion with granulomatous (histiocytic and multinucleate giant cell) infiltration. PMWS is considered as multifactorial disease, with a number of infectious and non-infectious factors able to act as disease triggering in PCV2 infected pigs. PCVDs are worldwide distributed, and PMWS was diagnosed in Macedonia in 2007.

Keywords: porcine circovirus type 2, postweaning multisystemic wasting syndrome


References


Citation Information

Macedonian Veterinary Review. Volume 32, Issue 1, Pages 5-11, ISSN 1409-7621, 2009