Case Report
Case report of canine co-infection with Leishmania infantum and Ehrlichia canis
Atanaskova Elena * ,
Kocevski Zoran ,
Nikolovski Goran ,
Stefanovska Jovana

Mac Vet Rev 2011; 34 (1): 19 - 24

636.7.09.[616.98.579.881.3.083.3

Received: 15 March 2011

Received in revised form: 15 March 2011

Accepted: 15 March 2011

Available Online First: 15 March 2011

Published on: 15 March 2011

Correspondence: Atanaskova Elena,
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Abstract

Canine leishmaniasis (CanL) due to Leishmania infantum and canine monocytic ehrilichiosis (CME) due to Ehrlichia canis are common diseases with zoonotic potential in the Mediterranean area. Their prevalence in R. Macedonia as a neighboring Mediterranean county is expected. In both diseases similar clinical symptoms can be manifested in dogs such as: lethargy, anorexia, weight loss, epistaxis, fever, pale mucous membranes, enlarged lymph nodes, splenomegaly, ocular signs. This case report present an atypical case of 11 year old female Samoyed with starting single clinical symptom epistaxys. Initial diagnostic procedures revealed the presence only of CanL, which was diagnosed using indirect immunofl uorescence method and ELISA. First laboratory fi ndings showed normal hematological and renal profi les. Dog was put on a treatment with Allopurinol (20mg/kg, p/o) for at least 9 months. Termination of the therapy after 6 months brought a numerous clinical symptoms involving weakness, dehydration, pale mucous membranes lost pupilar refl ex, uremic breath and biochemical parameters revealed a renal failure. Using a commercial ELISA kit Ehrlichia canis as a co infection was diagnosed. Most probably the second infectious agent was induced in the past 6 months, causing more severe pathological effects than CanL infection alone.

Keywords: L. infantum, Ehrichia canis, dog, IFAT, ELISA


References


Citation Information

Macedonian Veterinary Review. Volume 34, Issue 1, Pages 19-24, p-ISSN 1409-7621, e-ISSN 1857-7415, 2011