Original Scientific Article
Effect of storage on residue levels of enrofloxacin in muscle of rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio)
Ralica Kyuchukova * ,
Anelia Milanova ,
Aleksandra Daskalova ,
Deyan Stratev ,
Lubomir Lashev ,
Alexander Pavlov

Mac Vet Rev 2016; 39 (1): 97 - 102

10.1515/macvetrev-2016-0076

Received: 23 September 2015

Received in revised form: 05 January 2016

Accepted: 25 January 2016

Available Online First: 05 February 2016

Published on: 15 March 2016

Correspondence: Ralica Kyuchukova, ralitsa.kjuchukova@abv.bg
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Abstract

Since fluoroquinolones are one of the most commonly used antibacterial drugs in aquaculture, there is a risk of their residues to be found in the treated fish. The objective of this study was to examine t he changes in enrofloxacin and ciprofloxacin levelsduring storage of rainbow trout and common carp muscle at -18 °C. The trout and carp were treated orally with a single dose of 10 mg/kg of enrofloxacin. Tissue samples were collected 24 h after the treatment and stored at -18 °C for 270 days either as a whole fish or as precut muscle samples. Results for trout revealed that in the precut samples enrofloxacin concentration decreased significantly only after 9 months of storage, whereas a significant decline in the ciprofloxacin level was observed much earlier (after 3 months). After 9 months of storage, the trout stored without being sliced and eviscerated showed significantly higher levels of both quinolones as compared to the precut muscle samples. The enrofloxacin levels in the carp musculature decreased considerably after 3 months of storage and stayed almost unchanged up to the end of the study, whereas the ciprofloxacin concentration continued to drop even after this period and after 270 days constituted 1/6 of the initial values.

Keywords: ciprofloxacin, common carp, enrofloxacin, rainbow trout, residues, storage

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Copyright

© 2016 Kyuchukova R. This is an open-access article published under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Conflict of Interest Statement

The authors declared that they have no potential conflict of interest with respect to the authorship and/or publication of this article.

Citation Information

Macedonian Veterinary Review. Volume 39, Issue 1, Pages 97-102, p-ISSN 1409-7621, e-ISSN 1857-7415, DOI: 10.1515/macvetrev-2016-0076, 2016

The all content of the Macedonian Veterinary Review, except where otherwise noted, is licensed under a Creative Commons Attribution License.