Original Scientific Article
Time-dependent testicular and epididymal damage in rabbit bucks experimentally infected with Trypanosoma brucei brucei
Adewale Ayodeji Adeyeye*,
Musbaudeen Olayinka Alayande,
Monsurat Bansima Adio,
Lauratu Lawal Haliru,
Aliyu Abdulrafiu

Mac Vet Rev 2021; 44 (2): 139 - 147

10.2478/macvetrev-2021-0018

Received: 23 October 2020

Received in revised form: 09 February 2021

Accepted: 18 March 2021

Available Online First: 19 May 2021

Published on: 15 October 2021

Correspondence: Adewale Ayodeji Adeyeye, adewale.adeyeye@udusok.edu.ng

Abstract

This study was designed to determine the progressive pathological changes in the testis and epididymis of rabbit bucks experimentally infected with Trypanosoma brucei brucei (T. brucei). Fifteen local rabbit bucks were divided into 2 groups comprising 8 bucks in group A and 7 bucks in group B. Bucks in group A were infected intraperitoneally with approximately 1.0x106 of T. brucei while bucks in group B served as the uninfected control. The bucks were closely monitored for clinical signs of trypanosomosis from the time of infection till the end of the study. One buck from each group was humanely sacrificed on days 9, 19, 29 and 38 post-infection (pi) and its testis and epididymis were examined for pathological changes. At post mortem, no gross lesions were observed in the infected bucks except for adhesion of the testis and epididymis to the scrotum on days 29 and 38 pi. There were no histological changes in the testis and epididymis of the infected buck sacrificed on day 9 pi apart from mild depletion of the epididymal sperm reserve. The buck infected on day 19 pi had moderate testicular degeneration but the epididymis was devoid of sperm reserve. Severe testicular and epididymal degeneration was observed in the buck on days 29 and 38 pi. The testis and epididymis of bucks from the control group were normal with evidence of spermatogenic activities and full epididymal sperm reserve throughout. The study shows that infected bucks were unfit for breeding from day 19 pi.

Keywords: epididymis, rabbit buck, sperm reserve, testis, Trypanosoma brucei brucei


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Copyright

© 2021 Adeyeye A.A. This is an open-access article published under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Conflict of Interest Statement

The authors have declared that no competing interests exist.

Citation Information

Macedonian Veterinary Review. Volume 44, Issue 2, Pages 139-147, e-ISSN 1857-7415, p-ISSN 1409-7621, DOI: 10.2478/macvetrev-2021-0018, 2021