Short Communications
First report of bovine coenurosis in North Macedonia
Aleksandar Cvetkovikj * ,
Ljubica Rashikj ,
Boris Dimitrievski ,
Aleksandar Trajchovski ,
Ivana Shikoska ,
Petre Dimov ,
Iskra Cvetkovikj ,
Jovana Stefanovska

Mac Vet Rev 2024; 47 (1): 65 - 70


Received: 03 August 2023

Received in revised form: 15 October 2023

Accepted: 04 December 2023

Available Online First: 29 December 2023

Published on: 15 March 2024

Correspondence: Aleksandar Cvetkovikj,


Coenurosis is a cystic parasitic disease affecting ruminants and other mammals worldwide. The disease is caused by Coenurus cerebralis, the larval stage of the tapeworm Taenia multiceps. Sheep and goats are frequently infected, while cases in cattle are rare. Here we describe the first recorded case of bovine coenurosis in North Macedonia. The diagnosis was based on the neurological clinical signs and the postmortem findings of a 1-year-old bull with symptoms typical for coenurosis, i.e. ataxia, circling movements, mild depression and impaired vision. Postmortem, a cyst was found in the left cerebral hemisphere and was confirmed as fertile Coenurus cerebralis by parasitological analysis. These findings suggest that coenurosis should be considered part of the differential diagnosis in cattle with neurological symptoms. This highlights the need for routine surveillance of this disease in livestock and proactive tracking of the parasite in the final hosts to enhance disease management.

Keywords: Coenurus cerebralis, Taenia multiceps, cyst, cattle, zoonosis


1. Varcasia, A., Tamponi, C., Ahmed, F., Cappai, M.G., Porcu, F., Mehmood, N., Dessì, G., Scala, A. (2022). Taenia multiceps coenurosis: a review. Parasit Vectors. 15 (1): 84.  PMid:35279199 PMCid:PMC8917661
2. Giadinis, N.D., Brellou, G., Pourliotis, K., Papazahariadou, M., Sofianidis, G., Poutahidis, T., Panousis, N. (2007). Coenurosis in a beef cattle herd in Greece. Vet Rec. 161(20): 697-698. PMid:18024927
3. Avcioglu, H., Yildirim, A., Duzlu, O., Inci, A., Terim, K.A.K., Balkaya, I. (2011). Prevalence and molecular characterization of bovine coenurosis from Eastern Anatolian region of Turkey. Vet Parasitol. 176(1): 59-64. PMid:21074326
4. Varcasia, A., Pipia, A.P., Arru, D., Pes, A.M., Tamponi, C., Dore, F., Garippa, G., Scala, A. (2013). Morphological and molecular characterization of bovine coenurosis in Sardinia, Italy. Parasitol Res. 112(5): 2079-2082. PMid:23274489
5. Varcasia, A., Pipia, A.P., Dessì, G., Zidda, A., Tamponi, C., Pau, M., Scala, A., Boufana, B. (2016). Morphology and genetic variability within Taenia multiceps in ruminants from Italy. Vet Parasitol. 223, 181-185. PMid:27198798
6. Oryan, A., Akbari, M., Moazeni, M., Amrabadi, O.R. (2014). Cerebral and non-cerebral Coenurosis in small ruminants. Trop Biomed. 31(1): 1-16.
7. Avcioglu, H., Terim Kapakin, K.A., Yildirim, A. (2012). Clinical, morphological and histopathological features of bovine coenurosis: Case reports. Rev Med Vet. 163(6): 295-298.
8. Özkan, C., Yildirim, S., Kaya, A. (2011). Clinical coenurosis (Coenurus cerebralis) and associated pathological findings in a calf. Pak Vet J. 31(3): 263-266.
9. Giadinis, N.D., Panousis, N., Karatzias, H., Papazahariadou, M., Polizopoulou, Z. (2009). Cerebellar dysfunction in a calf with chronic coenurosis. Vet Rec. 164(16): 505-506. PMid:19377093
10. Greig, A., Holmes, E. (1977). Coenurosis in cattle. Vet Rec. 100(13): 266. PMid:860380
11. Yoshino, T., Momotani, E. (1988). A case of bovine coenurosis (Coenurus cerebralis) in Japan. Nihon Juigaku Zasshi. 50(2): 433-438. PMid:3386098
12. Moghaddar, N., Oryan, A., Gaur, S.N.S. (1992). Coenurosis in cattle in Iran. J Appl Anim Res. 2(2): 119-121. 
13. Islam, A., Rahman, M. (1997). A report on incidence of gid of calves of Bangladesh. Indian J Anim Heal. 36, 187-188.
14. Dinev, I., Stoykov, D., Bozadjiev, I. (1999). Clinical and morphological studies in spontaneous coenurosis in calves. Bulg J Vet Med. 2(2-3): 131-136.
15. Buroni, F., Armua-Fernandez, T., Nan, F., Matto, C., Venzal, J., Rivero, R. (2017). Coenurosis in cattle in Uruguay. Veterinaria (Montevideo) 54, 19-24.
16. Giaretta, P., Panziera, W., de Galiza, G., Barros, C. (2021). Bovine coenurosis. Braz J Vet Pathol. 14(3): 213-218. 
17. Ferreira, J., Riet-Correa, F., Schild, A., Méndez, M. (1992). Coenurosis in cattle in Rio Grande do Sul, Brazil. Rev Bras Parasitol Vet. 1, 113-116.
18. Sharma, D.K., Chauhan, P.P.S. (2006). Coenurosis status in Afro-Asian region: A review. Small Rumin Res. 64(3): 197-202. 
19. El-On, J., Shelef, I., Cagnano, E., Benifla, M. (2008). Taenia multiceps: a rare human cestode infection in Israel. Vet Ital. 44(4): 621-631.
20. Alvarez Rojas, C.A., Mathis, A., Deplazes, P. (2018). Assessing the contamination of food and the environment with Taenia and Echinococcus eggs and their zoonotic transmission. Curr Clin Microbiol Rep. 5, 154-163. 


© 2023 Cvetkovikj A. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Conflict of Interest Statement

The authors declared that they have no potential lict of interest with respect to the authorship and/or publication of this article.

Citation Information

Macedonian Veterinary Review. Volume 47, Issue 1, Pages 65-70, e-ISSN 1857-7415, p-ISSN 1409-7621, DOI: 10.2478/macvetrev-2023-0029