Diffuse cutaneous mastocytosis (pigmented maculopapular cutaneous mastocytosis) in a cat
Marcin Szczepanik
*
,
Piotr Wilkołek
,
Anna Śmiech
,
Iwona Taszkun
Received: 28 May 2019
Received in revised form: 13 August 2019
Accepted: 02 September 2019
Available Online First: 25 October 2019
Published on: 15 March 2020
Correspondence: Marcin Szczepanik, kryll@poczta.onet.pl
Abstract
Diffuse cutaneous mastocytosis was diagnosed in a 6-year-old, indoor, neutered female domestic European shorthair cat. Marked pruritus located mainly on the head and neck was noticed in the cat and in this area the animal had developed alopecia, crusts, and plaques. Histologically, monomorphic mast cells were found in the superficial dermis and around the hair follicles. Mast cells were well differentiated, with central nuclei and granular cytoplasm, with metachromatic granules which stained positively with Toluidine blue stain. The animal was successfully treated with oclacitinib at a dose of 1 mg/kg, twice a day per os.
Keywords: dermatology, mastocytosis, oclacitinib, cats
References
-
-
Gross, T., Ihrke, P., Walder, E. (2005). Mast cell tumors. In: Skin diseases of the dog and cat: Clinical and histopathologic diagnosis. (pp. 853-865). Oxford: Blackwell Science.
https://doi.org/10.1002/9780470752487
-
-
Tomich, L. M., Pieper, J. B. (2019). Urticaria pigmentosa-like skin disease in a domestic shorthair cat. J. Feline Med Surg Open Reports. 5(1): 1-4.
https://doi.org/10.1177/2055116918821197 PMid:30671254 PMCid:PMC6327337
-
Frank, R.K., Galvan, B.A., Schoell, A.R. (2014). Use of oclacitinib (Apoquel, Zoetis) for treatment of cutaneous mastocytosis in a cat. Vet Dermatol. 25, 153.
https://doi.org/10.1111/vde.12131
-
Ngo, J, Morren, MA, Bodemer, C, Heimann, M, Fontaine, J. (2019). Feline maculopapular cutaneous mastocytosis: a retrospective study of 13 cases and proposal for a new classification. J Feline Med Surg. 21, 394- 404.
https://doi.org/10.1177/1098612X18776141 PMid:29860905
-
Colombo, S., Scarampella, F., Ordeix, L., Roccabianca, P. (2012). Dermatophytosis and papular eosinophilic/mastocytic dermatitis (urticaria pigmentosa-like dermatitis) in three Devon Rex cats. J Feline Med Surg. 14, 498-502.
https://doi.org/10.1177/1098612X12440761 PMid:22736683
Copyright
© 2019 Szczepanik M. This is an open-access article published under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Conflict of Interest Statement
The authors have declared that no competing interests exist.
Citation Information
Macedonian Veterinary Review. Volume 43, Issue 1, Pages 81-83, p-ISSN 1409-7621, e-ISSN 1857-7415, DOI: 10.2478/macvetrev-2019-0025, 2020